Thymosin fragment (research)
TB-500
Lyophilized research peptide
Synthetic thymosin beta-4 fragment widely studied in vitro for actin-binding and migration assays. Lyophilized, ≥99% HPLC. Research use only.
Lab name and RUO acknowledgment are collected at checkout.
Lot documentation
Every shipment includes the lot-specific certificate of analysis — HPLC purity (≥99% typical), mass-spec identity, net peptide content, water content, and residual solvents.
Identity & specifications
- Common name
- TB-500 (Thymosin Beta-4 fragment)
- Sequence (Tβ4 17–23 motif)
- LKKTETQ — published synthetic analogue
- Molecular weight
- 4,963 g/mol (full Tβ4); fragment MW listed on CoA
- CAS
- 77591-33-4 (Tβ4 parent)
- Appearance
- White lyophilized powder
- Purity (HPLC)
- ≥ 99%
- Net peptide
- Listed on CoA
- Solubility
- Soluble in bacteriostatic or sterile water
TB-500 in laboratory research
TB-500 is a synthetic peptide corresponding to the active region of Thymosin Beta-4 (Tβ4). Tβ4 is a 43-residue G-actin sequestering protein extensively studied in vitro for its role in cytoskeletal dynamics, cell migration, and angiogenesis pathways across mammalian cell models. Synthetic TB-500 is used by labs as a sequence-defined surrogate for the active region in cell-culture and biochemical assays.
Identity and characterization
TB-500 ships with HPLC purity and mass-spectrometry identity data on the certificate of analysis. Labs running comparative work commonly pair TB-500 with a Tβ4-positive reference and a scrambled-sequence negative control; this listing is structured so your QA team can attach those references to the SKU in your procurement system.
Storage
Hold lyophilized vials at -20 °C protected from light. Reconstituted aliquots should be stored at 2-8 °C for short-term use or frozen in single-use working volumes. Do not subject reconstituted material to repeated freeze/thaw — peptide bond integrity is best preserved by aliquot planning before initial reconstitution.
Documentation
CoA, batch records, and a moisture/residuals summary where in scope. Documentation is filed by SKU and lot so procurement and EHS teams can retrieve records during audit.
Research guide
TB-500 research overview
TB-500 is a research-use-only material for qualified laboratory programs. This page summarizes identity fields, storage and handling, CoA review, and linked research resources for procurement and QA.
Catalog class: Thymosin fragment (research).
Key identity fields
- Common name
- TB-500 (Thymosin Beta-4 fragment)
- Sequence (Tβ4 17–23 motif)
- LKKTETQ — published synthetic analogue
- Molecular weight
- 4,963 g/mol (full Tβ4); fragment MW listed on CoA
- CAS
- 77591-33-4 (Tβ4 parent)
- Appearance
- White lyophilized powder
- Purity (HPLC)
- ≥ 99%
Storage and handling
Handle TB-500 as a lyophilized research reagent: cold, dry, light-protected storage; choose reconstitution buffer per your SOP; plan aliquots to limit freeze–thaw; and keep the lot CoA with the inventory record.
Research framing
Use TB-500 in published model-system terms only — receptor family, pathway context, assay controls, and concentration planning. Do not transfer assumptions from adjacent peptides without a documented comparison protocol. Research use only.
Documentation checklist
- Storage and stability records for the received lot
- Lot CoA with HPLC, MS identity, and net peptide content
- Literature and assay context filed with the protocol
- Verify lots in the CoA Library
Product FAQ
Is TB-500 intended for human or clinical use?
No. BluGen listings are research use only (RUO) for qualified laboratory programs — not clinical, diagnostic, therapeutic, veterinary, food, drug, or cosmetic use.
What documentation ships with TB-500?
Each lot includes a certificate of analysis with HPLC purity, MS identity confirmation, and net peptide content. Verify lots in the CoA Library.
Where can I verify the current-lot CoA for TB-500?
Search by compound or lot number in the CoA Library: https://getblugen.com/coa-library/
What sequence is listed for TB-500?
Verify sequence identity on the lot-specific CoA and identity table before use.
How should lyophilized TB-500 be stored?
Store sealed vials cold, dry, and protected from light per the lot CoA and your institutional SOP. Aliquot reconstituted stock to limit freeze-thaw cycles.
Can institutions request a quote for TB-500?
Yes. Academic labs and CROs can request quotes and NET-30 billing after vendor qualification via the contact/procurement desk.
Where is the research guide for TB-500?
See the BluGen research guide for literature context, storage notes, and comparisons: https://getblugen.com/research/research-guide-tb-500/
Related research resources
- TB-500 research guide
- Research peptide glossary
- Peptide reconstitution guide
- Peptide storage and reconstitution guide
- How to read a peptide CoA
- HPLC, MS, and net peptide content guide
- Research use only procurement guide
- Related comparison guide
- How to verify a peptide lot
- Supplier evaluation checklist
- Documentation hub
- Sample CoA field guide
Lab checklist
- Confirm lot CoA: HPLC purity, MS identity, and net peptide content before release.
- Record storage, reconstitution, concentration, and aliquot history per your SOP.
- Reconstitution calculator
- Documentation & verification hub
- Search PubMed for TB-500 research
Research use only (RUO)
This material is sold for laboratory research purposes only. It is not for clinical, diagnostic, therapeutic, or veterinary application, and not for food, drug, or cosmetic use where restricted.
Related research & procurement docs
Research-use-only guides, comparisons, and procurement briefs tagged to this compound.