GHRH analogue (research)
CJC-1295 (No DAC)
Lyophilized research peptide
Modified GRF(1-29) analogue without Drug Affinity Complex. Studied in vitro for GHRH-receptor binding and short-half-life signaling research. ≥99% HPLC. Research use only.
Lab name and RUO acknowledgment are collected at checkout.
Lot documentation
Every shipment includes the lot-specific certificate of analysis — HPLC purity (≥99% typical), mass-spec identity, net peptide content, water content, and residual solvents.
Identity & specifications
- Common name
- CJC-1295 No DAC (Modified GRF 1-29)
- Sequence
- H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
- Length
- 29 residues
- Molecular formula
- C152H252N44O42
- Molecular weight
- 3,367.95 g/mol
- Appearance
- White lyophilized powder
- Purity (HPLC)
- ≥ 99%
- Net peptide
- Listed on CoA
- Solubility
- Soluble in bacteriostatic water
CJC-1295 (No DAC) in research
CJC-1295 without DAC, also known as Modified GRF(1-29), is a 29-residue GHRH analogue carrying four substitutions (D-Ala-2, Gln-8, Ala-15, Leu-27) that improve in vitro plasma stability relative to native GHRH while retaining activity at the GHRH receptor. Published research uses the peptide as a sequence-defined GHRH-R reference reagent in cell-line and ex-vivo pituitary preparations.
Differentiator vs the DAC variant
The "No DAC" form omits the Lys-30 maleimidopropionyl group that covalently binds albumin in the DAC variant. Research labs choose No DAC when they need a short-half-life GHRH analogue for time-course studies; the DAC variant is preferred when extended half-life dynamics are the subject. CoA reports identity (MS) and purity (HPLC) covering both backbone and absence of the DAC modification.
Laboratory storage and reconstitution
Hold lyophilized vials sealed at -20 °C protected from light. Reconstitute with bacteriostatic water for laboratory use; aliquot reconstituted stock into single-use working volumes before freezing. Avoid repeated freeze/thaw.
Documentation
CoA covers identity (MS), purity (HPLC), and net peptide content. Batch records by lot are filed against the SKU for procurement and compliance review.
Research guide
CJC-1295 (No DAC) research overview
CJC-1295 (No DAC) is listed as a research-use-only material for qualified laboratory programs. This page connects the product listing with identity fields, storage context, CoA review, and long-form research resources so procurement and QA reviewers can evaluate the SKU without relying on a thin commerce page.
The catalog classifies this material as GHRH analogue (research), which helps labs compare it with adjacent research peptides, organize internal inventory, and build study-specific reference groups.
Key identity fields
- Common name
- CJC-1295 No DAC (Modified GRF 1-29)
- Sequence
- H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
- Length
- 29 residues
- Molecular formula
- C152H252N44O42
- Molecular weight
- 3,367.95 g/mol
- Appearance
- White lyophilized powder
Storage and handling context
For long-tail stability searches, CJC-1295 (No DAC) should be evaluated in the context of lyophilized storage, reconstitution buffer choice, aliquot planning, freeze-thaw limits, and lot-specific CoA conditions. Always follow institutional SOPs and the documentation attached to the received lot.
Mechanism context
CJC-1295 (No DAC) should be described through published model-system language: receptor family, pathway context, assay controls, concentration planning, and lot traceability. Avoid transferring assumptions from adjacent peptides without a documented comparison protocol.
Search intent covered
- CJC-1295 (No DAC) storage and stability
- CJC-1295 (No DAC) CoA and identity
- CJC-1295 (No DAC) mechanism research
- CJC-1295 (No DAC) comparison resources
Product FAQ
Is CJC-1295 (No DAC) intended for clinical programs?
No. BluGen listings are research use only (RUO) materials for qualified laboratory programs, not clinical, diagnostic, therapeutic, veterinary, food, drug, or cosmetic use.
What documentation is available for CJC-1295 (No DAC)?
Lot-level documentation may include CoA, HPLC purity, MS identity confirmation, net peptide content, and batch records where available for the SKU and lot.
How should lyophilized CJC-1295 (No DAC) be stored?
Store sealed lyophilized vials cold, dry, and protected from light unless the lot CoA or institutional SOP specifies another condition. Reconstituted material should be aliquoted according to the lab protocol.
Where can I learn more about CJC-1295 (No DAC) research context?
See the BluGen research guide for mechanism context, stability notes, storage considerations, and related peptide comparisons: https://getblugen.com/research/research-guide-cjc-1295-no-dac/
What is the research category for CJC-1295 (No DAC)?
CJC-1295 (No DAC) is categorized as GHRH analogue (research) for catalog organization, internal linking, and related research comparisons.
What sequence is listed for CJC-1295 (No DAC)?
The listed sequence for CJC-1295 (No DAC) is H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2. Always verify sequence and identity against the lot-specific CoA before use in a research workflow.
What molecular weight is listed for CJC-1295 (No DAC)?
The listed molecular weight for CJC-1295 (No DAC) is 3,367.95 g/mol. Use the lot CoA and net peptide content when calculating research stock concentrations.
Does CJC-1295 (No DAC) require cold storage?
Most lyophilized research peptides are stored cold, dry, sealed, and protected from light unless the lot CoA or institutional SOP states otherwise.
How should reconstituted CJC-1295 (No DAC) be handled?
Reconstituted research stocks should be labeled with SKU, lot, solvent, concentration, date, and technician initials, then aliquoted according to the lab protocol to limit freeze-thaw history.
Can lots of CJC-1295 (No DAC) be mixed together?
Avoid mixing lots unless a written protocol requires it. Mixed-lot stocks reduce traceability and make CoA review more difficult.
What purity documentation matters for CJC-1295 (No DAC)?
HPLC purity, MS identity, net peptide content, moisture or residual summaries where available, and lot number alignment are the core documentation checks.
What does net peptide content mean for CJC-1295 (No DAC)?
Net peptide content accounts for peptide mass apart from water and counter-ion contribution. It is important for molarity calculations in laboratory records.
What should procurement review before ordering CJC-1295 (No DAC)?
Procurement should review SKU, vial size, lot documentation path, RUO status, storage requirements, shipping expectations, and any internal approval requirements.
How should CJC-1295 (No DAC) be cited in a method record?
Record supplier, SKU, lot number, CoA document ID, reconstitution solvent, stock concentration, storage condition, and date prepared.
What are common related resources for CJC-1295 (No DAC)?
Related resources include the peptide storage guide, reconstitution guide, CoA reading guide, purity guide, and any comparison articles linked from the product page.
Why does BluGen link CJC-1295 (No DAC) to research articles?
Internal article links help buyers evaluate identity, storage, documentation, and research context without relying on a thin product listing.
What should be done if CJC-1295 (No DAC) documentation is incomplete?
Hold the lot in review and request the missing CoA or batch documentation before releasing the material into an internal research workflow.
Is CJC-1295 (No DAC) content on BluGen medical advice?
No. BluGen content is laboratory procurement and research documentation content for RUO materials only.
Related research resources
Reference path
- Lot CoA: verify HPLC purity, MS identity, and net peptide before release.
- Internal SOP: record storage, reconstitution, concentration, and aliquot history.
- Reconstitution calculator: convert vial size + diluent to concentration
- Article links: file the product guide, glossary definition, storage guide, and comparison page beside procurement notes.
- Search PubMed for CJC-1295 (No DAC) research
Research use only (RUO)
This material is sold for laboratory research purposes only. It is not for clinical, diagnostic, therapeutic, or veterinary application, and not for food, drug, or cosmetic use where restricted.